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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK9
All Species:
26.97
Human Site:
Y521
Identified Species:
59.33
UniProt:
Q8TD19
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD19
NP_149107.4
979
107168
Y521
L
D
S
E
E
D
Y
Y
T
P
Q
K
V
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097546
979
107204
Y521
L
D
S
E
E
D
Y
Y
T
P
Q
K
V
D
V
Dog
Lupus familis
XP_547912
974
106819
Y521
L
D
S
E
E
D
Y
Y
T
P
Q
K
V
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1R7
984
107065
Y521
L
D
S
E
E
D
Y
Y
T
P
Q
R
V
D
V
Rat
Rattus norvegicus
NP_001100217
958
104862
Y520
L
D
S
E
E
D
Y
Y
T
P
Q
R
V
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506669
536
57599
Q128
F
N
K
L
G
L
N
Q
C
M
S
G
I
I
N
Chicken
Gallus gallus
XP_001235085
1086
118657
Y633
L
D
S
E
E
D
H
Y
T
P
Q
K
V
D
V
Frog
Xenopus laevis
Q7ZZC8
944
104521
Y503
L
D
S
E
D
D
V
Y
S
P
Q
K
V
E
V
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
H289
S
N
V
Q
A
G
P
H
G
R
P
G
G
W
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781356
721
79856
E313
S
Q
S
S
F
Q
A
E
T
V
P
V
V
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXT4
555
62879
D147
E
Q
D
I
R
L
G
D
F
G
L
A
K
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
95.7
N.A.
95
93.6
N.A.
44.8
76
69.5
24.1
N.A.
N.A.
N.A.
N.A.
40.2
Protein Similarity:
100
N.A.
99.4
96.8
N.A.
96.4
95
N.A.
48.9
81.4
80.1
41
N.A.
N.A.
N.A.
N.A.
52.8
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
0
93.3
73.3
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
100
93.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
64
10
0
10
64
0
10
0
0
0
0
0
55
0
% D
% Glu:
10
0
0
64
55
0
0
10
0
0
0
0
0
10
0
% E
% Phe:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
10
10
10
0
10
10
0
19
10
0
0
% G
% His:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
10
19
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
46
10
0
0
% K
% Leu:
64
0
0
10
0
19
0
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
0
64
19
0
0
0
0
% P
% Gln:
0
19
0
10
0
10
0
10
0
0
64
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
0
19
0
0
0
% R
% Ser:
19
0
73
10
0
0
0
0
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
64
0
0
0
0
10
0
% T
% Val:
0
0
10
0
0
0
10
0
0
10
0
10
73
0
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
46
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _